2x26

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{{Seed}}
 
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[[Image:2x26.jpg|left|200px]]
 
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==Crystal structure of the periplasmic aliphatic sulphonate binding protein SsuA from Escherichia coli==
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The line below this paragraph, containing "STRUCTURE_2x26", creates the "Structure Box" on the page.
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<StructureSection load='2x26' size='340' side='right'caption='[[2x26]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2x26]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X26 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_2x26| PDB=2x26 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x26 OCA], [https://pdbe.org/2x26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x26 RCSB], [https://www.ebi.ac.uk/pdbsum/2x26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x26 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SSUA_ECOLI SSUA_ECOLI] Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x2/2x26_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x26 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Sulfur is an essential component for the biosynthesis of the sulfur-containing amino acids L-methionine and L-cysteine. Under sulfur-starvation conditions, bacteria are capable of scavenging sulfur from sulfur-containing compounds and transporting it across membranes. Here, the crystal structure of the periplasmic aliphatic sulfonate-binding protein SsuA from Escherichia coli is reported at 1.75 A resolution in the substrate-free state. The overall structure of SsuA resembles the structures of other periplasmic binding proteins and contains two globular domains that form a cleft. Comparison with other periplasmic binding proteins revealed that one of the domains has been displaced by a rigid movement of 17 degrees . Interestingly, the tight crystal packing appears to be mediated by a 13-amino-acid tail from the cloning that folds within the cleft of the next monomer.
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===CRYSTAL STRUCTURE OF THE PERIPLASMIC ALIPHATIC SULPHONATE BINDING PROTEIN SSUA FROM ESCHERICHIA COLI===
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Structure of the aliphatic sulfonate-binding protein SsuA from Escherichia coli.,Beale J, Lee SY, Iwata S, Beis K Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1;66(Pt, 4):391-6. Epub 2010 Mar 26. PMID:20383006<ref>PMID:20383006</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2X26 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X26 OCA].
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<div class="pdbe-citations 2x26" style="background-color:#fffaf0;"></div>
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[[Category: Escherichia coli]]
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== References ==
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[[Category: Beale, J.]]
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<references/>
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[[Category: Beis, K.]]
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__TOC__
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[[Category: Iwata, S.]]
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</StructureSection>
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[[Category: Lee, S.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Transport protein]]
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[[Category: Large Structures]]
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[[Category: Beale J]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:47:49 2010''
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[[Category: Beis K]]
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[[Category: Iwata S]]
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[[Category: Lee S]]

Current revision

Crystal structure of the periplasmic aliphatic sulphonate binding protein SsuA from Escherichia coli

PDB ID 2x26

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