3mji
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3mji is ON HOLD Authors: Pathak, M. C., Suresh, C. G., Dodson, G. G, Murshudov, G. N. Description: ACTIVATION OF CATALYTIC CYSTEINE WITHOUT A BASE ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor== | |
| + | <StructureSection load='3mji' size='340' side='right'caption='[[3mji]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3mji]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mji OCA], [https://pdbe.org/3mji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mji RCSB], [https://www.ebi.ac.uk/pdbsum/3mji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mji ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase. | ||
| - | + | ==See Also== | |
| - | + | *[[Penicillin acylase|Penicillin acylase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Lysinibacillus sphaericus]] | ||
| + | [[Category: Dodson GG]] | ||
| + | [[Category: Murshudov GN]] | ||
| + | [[Category: Pathak MC]] | ||
| + | [[Category: Suresh CG]] | ||
Current revision
Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor
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