3k75

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{{Seed}}
 
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[[Image:3k75.jpg|left|200px]]
 
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==X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain==
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The line below this paragraph, containing "STRUCTURE_3k75", creates the "Structure Box" on the page.
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<StructureSection load='3k75' size='340' side='right'caption='[[3k75]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3k75]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K75 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k75 OCA], [https://pdbe.org/3k75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k75 RCSB], [https://www.ebi.ac.uk/pdbsum/3k75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k75 ProSAT]</span></td></tr>
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{{STRUCTURE_3k75| PDB=3k75 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/XRCC1_HUMAN XRCC1_HUMAN] Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/3k75_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k75 ConSurf].
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<div style="clear:both"></div>
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===X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_20351257}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 20351257 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20351257}}
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==About this Structure==
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3K75 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K75 OCA].
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==Reference==
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<ref group="xtra">PMID:20351257</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Cuneo, M J.]]
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[[Category: Cuneo MJ]]
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[[Category: London, R E.]]
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[[Category: London RE]]
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[[Category: Allosteric disulfide]]
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[[Category: Dna damage]]
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[[Category: Dna repair]]
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[[Category: Dna replication]]
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[[Category: Dna synthesis]]
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[[Category: Dna-binding]]
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[[Category: Dna-binding protein]]
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[[Category: Dna-directed dna polymerase]]
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[[Category: Lyase]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Methylation]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Pol beta]]
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[[Category: Polymorphism]]
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[[Category: Sodium]]
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[[Category: Transferase]]
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[[Category: Ubl conjugation]]
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[[Category: Xrcc1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:55:39 2010''
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Current revision

X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain

PDB ID 3k75

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