3mmk
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3mmk is ON HOLD Authors: Gadd, M.S., Langley, D.B., Guss, J.M., Matthews, J.M. Description: Crystal Structure of Lhx4 LIM domains 1 and 2 with the ...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification== |
| - | + | <StructureSection load='3mmk' size='340' side='right'caption='[[3mmk]], [[Resolution|resolution]] 2.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3mmk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MMK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.157Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | '' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mmk OCA], [https://pdbe.org/3mmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mmk RCSB], [https://www.ebi.ac.uk/pdbsum/3mmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mmk ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LHX4_MOUSE LHX4_MOUSE] May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.[https://www.uniprot.org/uniprot/ISL2_MOUSE ISL2_MOUSE] Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Gadd MS]] | ||
| + | [[Category: Guss JM]] | ||
| + | [[Category: Langley DB]] | ||
| + | [[Category: Matthews JM]] | ||
Current revision
The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification
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