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2kvq

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{{Seed}}
 
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[[Image:2kvq.jpg|left|200px]]
 
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==Solution structure of NusE:NusG-CTD complex==
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The line below this paragraph, containing "STRUCTURE_2kvq", creates the "Structure Box" on the page.
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<StructureSection load='2kvq' size='340' side='right'caption='[[2kvq]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2kvq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KVQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kvq OCA], [https://pdbe.org/2kvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kvq RCSB], [https://www.ebi.ac.uk/pdbsum/2kvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kvq ProSAT]</span></td></tr>
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{{STRUCTURE_2kvq| PDB=2kvq | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RS10_ECOLI RS10_ECOLI] Involved in the binding of tRNA to the ribosomes.[HAMAP-Rule:MF_00508]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/2kvq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kvq ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Bacterial NusG is a highly conserved transcription factor that is required for most Rho activity in vivo. We show by nuclear magnetic resonance spectroscopy that Escherichia coli NusG carboxyl-terminal domain forms a complex alternatively with Rho or with transcription factor NusE, a protein identical to 30S ribosomal protein S10. Because NusG amino-terminal domain contacts RNA polymerase and the NusG carboxy-terminal domain interaction site of NusE is accessible in the ribosomal 30S subunit, NusG may act as a link between transcription and translation. Uncoupling of transcription and translation at the ends of bacterial operons enables transcription termination by Rho factor, and competition between ribosomal NusE and Rho for NusG helps to explain why Rho cannot terminate translated transcripts.
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===Solution structure of NusE:NusG-CTD complex===
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A NusE:NusG complex links transcription and translation.,Burmann BM, Schweimer K, Luo X, Wahl MC, Stitt BL, Gottesman ME, Rosch P Science. 2010 Apr 23;328(5977):501-4. PMID:20413501<ref>PMID:20413501</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_20413501}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2kvq" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 20413501 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_20413501}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Escherichia coli K-12]]
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2KVQ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVQ OCA].
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[[Category: Large Structures]]
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[[Category: Burmann BM]]
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==Reference==
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[[Category: Roesch P]]
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<ref group="xtra">PMID:20413501</ref><references group="xtra"/>
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[[Category: Schweimer K]]
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[[Category: Escherichia coli]]
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[[Category: Burmann, B M.]]
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[[Category: Roesch, P.]]
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[[Category: Schweimer, K.]]
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[[Category: Nuse:nusg complex]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 12:01:21 2010''
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Current revision

Solution structure of NusE:NusG-CTD complex

PDB ID 2kvq

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