3md3

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{{Seed}}
 
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[[Image:3md3.jpg|left|200px]]
 
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==Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)==
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The line below this paragraph, containing "STRUCTURE_3md3", creates the "Structure Box" on the page.
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<StructureSection load='3md3' size='340' side='right'caption='[[3md3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3md3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MD3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3md3| PDB=3md3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3md3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3md3 OCA], [https://pdbe.org/3md3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3md3 RCSB], [https://www.ebi.ac.uk/pdbsum/3md3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3md3 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)===
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== Function ==
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[https://www.uniprot.org/uniprot/PUB1_YEAST PUB1_YEAST] May be associated with hnRNA within the nucleus and remains associated during nucleocytoplasmic mRNA transport, once the proteins are in the cytoplasm, disassembly of PUB1-RNA complexes may occur prior to PAB1 binding and formation of a translationally competent RNP complex. Binds to polyadenylated RNA; prefers to bind poly(rU); binds to T-rich single-stranded DNA.
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3MD3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MD3 OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/3md3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3md3 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Li, H.]]
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[[Category: Li H]]
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[[Category: Niu, L.]]
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[[Category: Niu L]]
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[[Category: Shi, H.]]
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[[Category: Shi H]]
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[[Category: Teng, M.]]
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[[Category: Teng M]]
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[[Category: Wang, H.]]
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[[Category: Wang H]]
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[[Category: Zhu, Z.]]
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[[Category: Zhu Z]]
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[[Category: Acetylation]]
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[[Category: Cytoplasm]]
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[[Category: Nucleus]]
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[[Category: Rbd]]
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[[Category: Rna binding protein]]
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[[Category: Rna-binding]]
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[[Category: Rnp]]
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[[Category: Rrm]]
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[[Category: Tandem]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 12:11:45 2010''
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Current revision

Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)

PDB ID 3md3

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