3m66

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{{Seed}}
 
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[[Image:3m66.png|left|200px]]
 
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==Crystal structure of human Mitochondrial Transcription Termination Factor 3==
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The line below this paragraph, containing "STRUCTURE_3m66", creates the "Structure Box" on the page.
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<StructureSection load='3m66' size='340' side='right'caption='[[3m66]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3m66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M66 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m66 OCA], [https://pdbe.org/3m66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m66 RCSB], [https://www.ebi.ac.uk/pdbsum/3m66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m66 ProSAT]</span></td></tr>
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{{STRUCTURE_3m66| PDB=3m66 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of human Mitochondrial Transcription Termination Factor 3===
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[https://www.uniprot.org/uniprot/MTEF3_HUMAN MTEF3_HUMAN] Binds promoter DNA and regulates initiation of transcription (PubMed:17662942). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).[UniProtKB:Q8R3J4]<ref>PMID:17662942</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_20430012}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 20430012 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m6/3m66_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_20430012}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m66 ConSurf].
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3M66 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M66 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:20430012</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Gustafsson, C M.]]
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[[Category: Large Structures]]
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[[Category: Hallberg, B M.]]
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[[Category: Gustafsson CM]]
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[[Category: Samuelsson, T.]]
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[[Category: Hallberg BM]]
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[[Category: Spahr, H.]]
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[[Category: Samuelsson T]]
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[[Category: Dna binding protein]]
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[[Category: Spahr H]]
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[[Category: Mitochondrion]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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[[Category: Transcription termination]]
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[[Category: Transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:29:35 2010''
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Current revision

Crystal structure of human Mitochondrial Transcription Termination Factor 3

PDB ID 3m66

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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