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1vew

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[[Image:1vew.jpg|left|200px]]<br /><applet load="1vew" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1vew, resolution 2.1&Aring;" />
 
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'''MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI'''<br />
 
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==About this Structure==
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==MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI==
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1VEW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with MN and OH as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] Known structural/functional Sites: <scene name='pdbsite=MN1:Mn-Bound Active Site On Chain A. Catalytic Redox Center'>MN1</scene>, <scene name='pdbsite=MN2:Mn-Bound Active Site On Chain B. Catalytic Redox Center'>MN2</scene>, <scene name='pdbsite=MN3:Mn-Bound Active Site On Chain C. Catalytic Redox Center'>MN3</scene> and <scene name='pdbsite=MN4:Mn-Bound Active Site On Chain D. Catalytic Redox Center'>MN4</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VEW OCA].
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<StructureSection load='1vew' size='340' side='right'caption='[[1vew]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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[[Category: Escherichia coli]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1vew]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VEW FirstGlance]. <br>
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[[Category: Superoxide dismutase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Baker, E.N.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
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[[Category: Baker, H.M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vew OCA], [https://pdbe.org/1vew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vew RCSB], [https://www.ebi.ac.uk/pdbsum/1vew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vew ProSAT]</span></td></tr>
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[[Category: Edwards, R.A.]]
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</table>
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[[Category: Jameson, G.B.]]
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== Function ==
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[[Category: Whittaker, J.W.]]
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[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
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[[Category: Whittaker, M.M.]]
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== Evolutionary Conservation ==
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[[Category: MN]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: OH]]
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Check<jmol>
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[[Category: dna binding]]
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<jmolCheckbox>
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[[Category: manganese enzyme]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/1vew_consurf.spt"</scriptWhenChecked>
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[[Category: metalloprotein]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: oxidoreductase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: superoxide dismutase]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vew ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 18:22:13 2007''
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==See Also==
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Baker EN]]
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[[Category: Baker HM]]
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[[Category: Edwards RA]]
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[[Category: Jameson GB]]
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[[Category: Whittaker JW]]
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[[Category: Whittaker MM]]

Current revision

MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI

PDB ID 1vew

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