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3n0u
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3n0u is ON HOLD Authors: Cooper, David R., Roy, Ankoor, Derewenda, Zygmunt S., Integrated Center for Structure and Function Innovation (ISFI) Descr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima== | |
| + | <StructureSection load='3n0u' size='340' side='right'caption='[[3n0u]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3n0u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N0U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0u OCA], [https://pdbe.org/3n0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n0u RCSB], [https://www.ebi.ac.uk/pdbsum/3n0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n0u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OGG1_THEMA OGG1_THEMA] Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Thermotoga maritima]] | ||
| + | [[Category: Cooper DR]] | ||
| + | [[Category: Derewenda ZS]] | ||
| + | [[Category: Roy A]] | ||
Current revision
Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima
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