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3ko0

From Proteopedia

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{{Seed}}
 
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[[Image:3ko0.jpg|left|200px]]
 
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==Structure of the tfp-ca2+-bound activated form of the s100a4 Metastasis factor==
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The line below this paragraph, containing "STRUCTURE_3ko0", creates the "Structure Box" on the page.
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<StructureSection load='3ko0' size='340' side='right'caption='[[3ko0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ko0]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KO0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TFP:10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE'>TFP</scene></td></tr>
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{{STRUCTURE_3ko0| PDB=3ko0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ko0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko0 OCA], [https://pdbe.org/3ko0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ko0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ko0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ko0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S10A4_HUMAN S10A4_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/3ko0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ko0 ConSurf].
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<div style="clear:both"></div>
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===Structure of the tfp-ca2+-bound activated form of the s100a4 Metastasis factor===
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==See Also==
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*[[S100 proteins 3D structures|S100 proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_20421509}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 20421509 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20421509}}
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==About this Structure==
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3KO0 is a 20 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO0 OCA].
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==Reference==
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<ref group="xtra">PMID:20421509</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Almo, S C.]]
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[[Category: Large Structures]]
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[[Category: Bresnick, A R.]]
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[[Category: Almo SC]]
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[[Category: Dulyaninova, N G.]]
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[[Category: Bresnick AR]]
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[[Category: Knight, D.]]
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[[Category: Dulyaninova NG]]
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[[Category: Malashkevich, V N.]]
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[[Category: Knight D]]
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[[Category: Acetylation]]
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[[Category: Malashkevich VN]]
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[[Category: Ca2+]]
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[[Category: Calcium]]
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[[Category: Metal binding protein]]
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[[Category: Mts1]]
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[[Category: Oligomerization]]
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[[Category: S100a4]]
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[[Category: Tfp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:32:12 2010''
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Current revision

Structure of the tfp-ca2+-bound activated form of the s100a4 Metastasis factor

PDB ID 3ko0

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