103d

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[[Image:103d.png|left|200px]]
 
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==THE UNUSUAL STRUCTURE OF THE HUMAN CENTROMERE (GGA)2 MOTIF: UNPAIRED GUANOSINE RESIDUES STACKED BETWEEN SHEARED G(DOT)A PAIRS==
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The line below this paragraph, containing "STRUCTURE_103d", creates the "Structure Box" on the page.
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<StructureSection load='103d' size='340' side='right'caption='[[103d]]' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[103d]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=103D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=103D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=103d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=103d OCA], [https://pdbe.org/103d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=103d RCSB], [https://www.ebi.ac.uk/pdbsum/103d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=103d ProSAT]</span></td></tr>
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{{STRUCTURE_103d| PDB=103d | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The centromere of human chromosomes contains multiple repeats of the DNA sequence d(TGGAA)n. This sequence has the interesting property of pairing with itself to form stable duplexes. We have determined the solution structure of the unusual DNA duplex 5'-TGGAATGGAA:TGGAATGGAA-3' at atomic resolution. The duplex contains unpaired staggered guanosine residues, which co-stack by intercalation between sheared G.A and A.G base-pairs to form an interesting new structural motif, the GA-bracketed G-stack. The TGGAA repeat unit contains six "steps", four of which are not Watson-Crick base-pairs.
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===THE UNUSUAL STRUCTURE OF THE HUMAN CENTROMERE (GGA)2 MOTIF: UNPAIRED GUANOSINE RESIDUES STACKED BETWEEN SHEARED G(DOT)A PAIRS===
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The unusual structure of the human centromere (GGA)2 motif. Unpaired guanosine residues stacked between sheared G.A pairs.,Chou SH, Zhu L, Reid BR J Mol Biol. 1994 Dec 2;244(3):259-68. PMID:7966337<ref>PMID:7966337</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 103d" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 7966337 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_7966337}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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103D is a 2 chains structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=103D OCA].
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[[Category: Chou S-H]]
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[[Category: Reid BR]]
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==Reference==
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[[Category: Zhu L]]
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<ref group="xtra">PMID:7966337</ref><references group="xtra"/>
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[[Category: Chou, S H.]]
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[[Category: Reid, B R.]]
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[[Category: Zhu, L.]]
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[[Category: Dna]]
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[[Category: Double helix]]
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[[Category: G-g stacking]]
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[[Category: G:a mismatch]]
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[[Category: Ga-bracketed g-stack motif]]
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[[Category: Human centromere repeat]]
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[[Category: Nmr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 22:38:07 2010''
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Current revision

THE UNUSUAL STRUCTURE OF THE HUMAN CENTROMERE (GGA)2 MOTIF: UNPAIRED GUANOSINE RESIDUES STACKED BETWEEN SHEARED G(DOT)A PAIRS

PDB ID 103d

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