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3lzj

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{{Seed}}
 
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[[Image:3lzj.png|left|200px]]
 
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<!--
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==RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine==
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The line below this paragraph, containing "STRUCTURE_3lzj", creates the "Structure Box" on the page.
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<StructureSection load='3lzj' size='340' side='right'caption='[[3lzj]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lzj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8OG:8-OXO-2-DEOXY-GUANOSINE-5-MONOPHOSPHATE'>8OG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene></td></tr>
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{{STRUCTURE_3lzj| PDB=3lzj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lzj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lzj OCA], [https://pdbe.org/3lzj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lzj RCSB], [https://www.ebi.ac.uk/pdbsum/3lzj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lzj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lzj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lzj ConSurf].
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<div style="clear:both"></div>
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===RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_20411947}}, adds the Publication Abstract to the page
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[[Category: Escherichia phage RB69]]
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(as it appears on PubMed at http://www.pubmed.gov), where 20411947 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Beckman J]]
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{{ABSTRACT_PUBMED_20411947}}
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[[Category: Blaha G]]
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[[Category: Konigsberg WH]]
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==About this Structure==
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[[Category: Wang J]]
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3LZJ is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZJ OCA].
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[[Category: Wang M]]
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==Reference==
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<ref group="xtra">PMID:20411947</ref><references group="xtra"/>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Enterobacteria phage rb69]]
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[[Category: Beckman, J.]]
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[[Category: Blaha, G.]]
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[[Category: Konigsberg, W H.]]
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[[Category: Wang, J.]]
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[[Category: Wang, M.]]
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[[Category: 8-dihydro-8-oxoguanine]]
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[[Category: Dna polymerase]]
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[[Category: Polymerase-dna-dntp ternary complex]]
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[[Category: Replication fidelity]]
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[[Category: Transferase-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:07:09 2010''
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Current revision

RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine

PDB ID 3lzj

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