2rr6
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2rr6 is ON HOLD Authors: Tochio, N., Umehara, T., Tsuda, K., Koshiba, S., Harada, T., Watanabe, S., Tanaka, A., Kigawa, T., Yokoyama, S. Descriptio...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B== | |
| - | + | <StructureSection load='2rr6' size='340' side='right'caption='[[2rr6]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2rr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RR6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rr6 OCA], [https://pdbe.org/2rr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rr6 RCSB], [https://www.ebi.ac.uk/pdbsum/2rr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rr6 ProSAT]</span></td></tr> | |
| - | '' | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AN32B_HUMAN AN32B_HUMAN] Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.<ref>PMID:20538007</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rr/2rr6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rr6 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Harada T]] | ||
| + | [[Category: Kigawa T]] | ||
| + | [[Category: Koshiba S]] | ||
| + | [[Category: Tanaka A]] | ||
| + | [[Category: Tochio N]] | ||
| + | [[Category: Tsuda K]] | ||
| + | [[Category: Umehara T]] | ||
| + | [[Category: Watanabe S]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B
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Categories: Homo sapiens | Large Structures | Harada T | Kigawa T | Koshiba S | Tanaka A | Tochio N | Tsuda K | Umehara T | Watanabe S | Yokoyama S
