3n8e
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3n8e is ON HOLD Authors: Wisniewska, M., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, ...) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)== | |
| - | + | <StructureSection load='3n8e' size='340' side='right'caption='[[3n8e]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3n8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N8E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8e OCA], [https://pdbe.org/3n8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n8e RCSB], [https://www.ebi.ac.uk/pdbsum/3n8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8e ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GRP75_HUMAN GRP75_HUMAN] Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/3n8e_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n8e ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Berglund H]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Collins R]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Flodin S]] | ||
| + | [[Category: Flores A]] | ||
| + | [[Category: Graslund S]] | ||
| + | [[Category: Hammarstrom M]] | ||
| + | [[Category: Johansson I]] | ||
| + | [[Category: Karlberg T]] | ||
| + | [[Category: Kotenyova T]] | ||
| + | [[Category: Moche M]] | ||
| + | [[Category: Nordlund P]] | ||
| + | [[Category: Nyman T]] | ||
| + | [[Category: Persson C]] | ||
| + | [[Category: Schuler H]] | ||
| + | [[Category: Schutz P]] | ||
| + | [[Category: Siponen MI]] | ||
| + | [[Category: Svensson L]] | ||
| + | [[Category: Thorsell AG]] | ||
| + | [[Category: Tresaugues L]] | ||
| + | [[Category: Wahlberg E]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Welin M]] | ||
| + | [[Category: Wisniewska M]] | ||
| + | [[Category: Van der Berg S]] | ||
Current revision
Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berglund H | Bountra C | Collins R | Edwards AM | Flodin S | Flores A | Graslund S | Hammarstrom M | Johansson I | Karlberg T | Kotenyova T | Moche M | Nordlund P | Nyman T | Persson C | Schuler H | Schutz P | Siponen MI | Svensson L | Thorsell AG | Tresaugues L | Wahlberg E | Weigelt J | Welin M | Wisniewska M | Van der Berg S
