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3n93
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3n93 is ON HOLD Authors: Pal, Kuntal, Swaminathan, K., Pioszak, Augen A., Xu, H. E. Description: Crystal structure of human CRFR2 alpha extracellul...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3== | |
| - | + | <StructureSection load='3n93' size='340' side='right'caption='[[3n93]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3n93]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N93 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr> | |
| - | '' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n93 OCA], [https://pdbe.org/3n93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n93 RCSB], [https://www.ebi.ac.uk/pdbsum/3n93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n93 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UCN3_HUMAN UCN3_HUMAN] Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pal K]] | ||
| + | [[Category: Pioszak AA]] | ||
| + | [[Category: Swaminathan K]] | ||
| + | [[Category: Xu HE]] | ||
Current revision
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3
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