This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2rr6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:06, 1 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2rr6.jpg|left|200px]]
 
-
<!--
+
==Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B==
-
The line below this paragraph, containing "STRUCTURE_2rr6", creates the "Structure Box" on the page.
+
<StructureSection load='2rr6' size='340' side='right'caption='[[2rr6]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2rr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RR6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rr6 OCA], [https://pdbe.org/2rr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rr6 RCSB], [https://www.ebi.ac.uk/pdbsum/2rr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rr6 ProSAT]</span></td></tr>
-
{{STRUCTURE_2rr6| PDB=2rr6 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B===
+
[https://www.uniprot.org/uniprot/AN32B_HUMAN AN32B_HUMAN] Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.<ref>PMID:20538007</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
2RR6 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RR6 OCA].
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rr/2rr6_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rr6 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Harada, T.]]
+
[[Category: Large Structures]]
-
[[Category: Kigawa, T.]]
+
[[Category: Harada T]]
-
[[Category: Koshiba, S.]]
+
[[Category: Kigawa T]]
-
[[Category: Tanaka, A.]]
+
[[Category: Koshiba S]]
-
[[Category: Tochio, N.]]
+
[[Category: Tanaka A]]
-
[[Category: Tsuda, K.]]
+
[[Category: Tochio N]]
-
[[Category: Umehara, T.]]
+
[[Category: Tsuda K]]
-
[[Category: Watanabe, S.]]
+
[[Category: Umehara T]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Watanabe S]]
-
[[Category: Acidic protein rich in leucine]]
+
[[Category: Yokoyama S]]
-
[[Category: Gene regulation]]
+
-
[[Category: Phapi2 protein]]
+
-
[[Category: Rdc]]
+
-
[[Category: Silver-stainable protein ssp29]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 11:12:20 2010''
+

Current revision

Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B

PDB ID 2rr6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2rr6"
Personal tools