This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3nfz
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3nfz is ON HOLD Authors: Hsieh, Jennifer M., Tsirulnikov, Kirill, Sawaya, Michael R., Magilnick, Nathaniel, Abuladze, Natalia, Kurtz, Ira, Abramson,...) |
|||
| (10 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of murine aminoacylase 3 in complex with N-acetyl-L-tyrosine== | |
| + | <StructureSection load='3nfz' size='340' side='right'caption='[[3nfz]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3nfz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NFZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.147Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3NF:N-ACETYL-L-TYROSINE'>3NF</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nfz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfz OCA], [https://pdbe.org/3nfz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nfz RCSB], [https://www.ebi.ac.uk/pdbsum/3nfz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nfz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACY3_MOUSE ACY3_MOUSE] Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.<ref>PMID:14656720</ref> <ref>PMID:17012540</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminoacylase 3D structures|Aminoacylase 3D structures]] | |
| - | + | *[[Aspartoacylase 3D structures|Aspartoacylase 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Abramson J]] | ||
| + | [[Category: Abuladze N]] | ||
| + | [[Category: Hsieh JM]] | ||
| + | [[Category: Kurtz I]] | ||
| + | [[Category: Magilnick N]] | ||
| + | [[Category: Pushkin A]] | ||
| + | [[Category: Sawaya MR]] | ||
| + | [[Category: Tsirulnikov K]] | ||
Current revision
Crystal structure of murine aminoacylase 3 in complex with N-acetyl-L-tyrosine
| |||||||||||
Categories: Large Structures | Mus musculus | Abramson J | Abuladze N | Hsieh JM | Kurtz I | Magilnick N | Pushkin A | Sawaya MR | Tsirulnikov K
