2xd8

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{{Seed}}
 
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[[Image:2xd8.jpg|left|200px]]
 
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==Capsid structure of the infectious Prochlorococcus Cyanophage P-SSP7==
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The line below this paragraph, containing "STRUCTURE_2xd8", creates the "Structure Box" on the page.
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<SX load='2xd8' size='340' side='right' viewer='molstar' caption='[[2xd8]], [[Resolution|resolution]] 4.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2xd8]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Prochlorococcus_virus_PSSP7 Prochlorococcus virus PSSP7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd8 OCA], [https://pdbe.org/2xd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd8 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd8 ProSAT]</span></td></tr>
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{{STRUCTURE_2xd8| PDB=2xd8 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q58N30_BPPRP Q58N30_BPPRP]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xd8 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Podovirus P-SSP7 infects Prochlorococcus marinus, the most abundant oceanic photosynthetic microorganism. Single-particle cryo-electron microscopy yields icosahedral and asymmetrical structures of infectious P-SSP7 with 4.6-A and 9-A resolution, respectively. The asymmetric reconstruction reveals how symmetry mismatches are accommodated among five of the gene products at the portal vertex. Reconstructions of infectious and empty particles show a conformational change of the 'valve' density in the nozzle, an orientation difference in the tail fibers, a disordering of the C terminus of the portal protein and the disappearance of the core proteins. In addition, cryo-electron tomography of P-SSP7 infecting Prochlorococcus showed the same tail-fiber conformation as that in empty particles. Our observations suggest a mechanism whereby, upon binding to the host cell, the tail fibers induce a cascade of structural alterations of the portal vertex complex that triggers DNA release.
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===CAPSID STRUCTURE OF THE INFECTIOUS PROCHLOROCOCCUS CYANOPHAGE P-SSP7===
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Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus.,Liu X, Zhang Q, Murata K, Baker ML, Sullivan MB, Fu C, Dougherty MT, Schmid MF, Osburne MS, Chisholm SW, Chiu W Nat Struct Mol Biol. 2010 Jul;17(7):830-6. Epub 2010 Jun 13. PMID:20543830<ref>PMID:20543830</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2XD8 is a 7 chains structure with sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD8 OCA].
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<div class="pdbe-citations 2xd8" style="background-color:#fffaf0;"></div>
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[[Category: Viruses]]
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== References ==
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[[Category: Baker, M L.]]
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<references/>
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[[Category: Chisholm, S W.]]
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__TOC__
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[[Category: Chiu, W.]]
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</SX>
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[[Category: Dougherty, M.]]
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[[Category: Large Structures]]
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[[Category: Fu, C.]]
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[[Category: Prochlorococcus virus PSSP7]]
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[[Category: Liu, X.]]
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[[Category: Baker ML]]
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[[Category: Murata, K.]]
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[[Category: Chisholm SW]]
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[[Category: Osburne, M S.]]
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[[Category: Chiu W]]
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[[Category: Schmid, M F.]]
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[[Category: Dougherty M]]
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[[Category: Sullivan, M B.]]
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[[Category: Fu C]]
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[[Category: Zhang, Q.]]
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[[Category: Liu X]]
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[[Category: Marine podovirus]]
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[[Category: Murata K]]
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[[Category: T7-like virus]]
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[[Category: Osburne MS]]
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[[Category: Virus]]
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[[Category: Schmid MF]]
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[[Category: Sullivan MB]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:36:10 2010''
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[[Category: Zhang Q]]

Current revision

Capsid structure of the infectious Prochlorococcus Cyanophage P-SSP7

2xd8, resolution 4.60Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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