3m9m

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:05, 13 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3m9m.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of Dpo4 in complex with DNA containing the major cisplatin lesion==
-
The line below this paragraph, containing "STRUCTURE_3m9m", creates the "Structure Box" on the page.
+
<StructureSection load='3m9m' size='340' side='right'caption='[[3m9m]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3m9m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M9M FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
{{STRUCTURE_3m9m| PDB=3m9m | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m9m OCA], [https://pdbe.org/3m9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m9m RCSB], [https://www.ebi.ac.uk/pdbsum/3m9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m9m ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m9/3m9m_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m9m ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal Structure of Dpo4 in complex with DNA containing the major cisplatin lesion===
+
==See Also==
-
 
+
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_20512114}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 20512114 is the PubMed ID number.
+
[[Category: Saccharolobus solfataricus]]
-
-->
+
[[Category: Ling H]]
-
{{ABSTRACT_PUBMED_20512114}}
+
[[Category: Wong JHY]]
-
 
+
-
==About this Structure==
+
-
3M9M is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9M OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:20512114</ref><references group="xtra"/>
+
-
[[Category: DNA-directed DNA polymerase]]
+
-
[[Category: Sulfolobus solfataricus]]
+
-
[[Category: Ling, H.]]
+
-
[[Category: Wong, J H.Y.]]
+
-
[[Category: Cisplatin]]
+
-
[[Category: Cytoplasm]]
+
-
[[Category: Dna]]
+
-
[[Category: Dna damage]]
+
-
[[Category: Dna repair]]
+
-
[[Category: Dna replication]]
+
-
[[Category: Dna-binding]]
+
-
[[Category: Dna-directed dna polymerase]]
+
-
[[Category: Dpo4]]
+
-
[[Category: Magnesium]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Mutator protein]]
+
-
[[Category: Nucleotidyltransferase]]
+
-
[[Category: Protein-dna complex]]
+
-
[[Category: Tl]]
+
-
[[Category: Transferase]]
+
-
[[Category: Transferase-dna complex]]
+
-
[[Category: Translesion dna synthesis]]
+
-
[[Category: Y-family dna polymerase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:42:07 2010''
+

Current revision

Crystal Structure of Dpo4 in complex with DNA containing the major cisplatin lesion

PDB ID 3m9m

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3m9m"
Personal tools