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3n8h
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3n8h.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis== | |
| - | + | <StructureSection load='3n8h' size='340' side='right' caption='[[3n8h]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3n8h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fratt Fratt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N8H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTT_1390, panC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8h OCA], [http://pdbe.org/3n8h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n8h RCSB], [http://www.ebi.ac.uk/pdbsum/3n8h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8h ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | == | + | [[http://www.uniprot.org/uniprot/PANC_FRATT PANC_FRATT]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity). |
| - | + | == Evolutionary Conservation == | |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/3n8h_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n8h ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fratt]] | ||
[[Category: Pantoate--beta-alanine ligase]] | [[Category: Pantoate--beta-alanine ligase]] | ||
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: Joachimiak, A | + | [[Category: Structural genomic]] |
| - | [[Category: Kim, Y | + | [[Category: Joachimiak, A]] |
| - | [[Category: Maltseva, N | + | [[Category: Kim, Y]] |
| - | [[Category: Papazisi, L | + | [[Category: Maltseva, N]] |
| + | [[Category: Papazisi, L]] | ||
[[Category: Alpha-beta sandwich]] | [[Category: Alpha-beta sandwich]] | ||
| - | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Ligase]] | [[Category: Ligase]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics of infectious disease]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:44:29 2010'' | ||
Current revision
Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis
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