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3nkz
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3nkz is ON HOLD until Aug 05 2011 Authors: Tan, K., Li, H., Feldmann, B., Joachimiak, A., Midwest Center for Structural Genomics (MCSG) Description...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of a flagella protein from Yersinia enterocolitica subsp. enterocolitica 8081== |
| - | + | <StructureSection load='3nkz' size='340' side='right' caption='[[3nkz]], [[Resolution|resolution]] 2.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3nkz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Yere8 Yere8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NKZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fliT, YE2526 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=393305 YERE8])</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nkz OCA], [http://pdbe.org/3nkz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nkz RCSB], [http://www.ebi.ac.uk/pdbsum/3nkz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nkz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FLIT_YERE8 FLIT_YERE8]] Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/3nkz_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nkz ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Yere8]] | ||
| + | [[Category: Feldmann, B]] | ||
| + | [[Category: Joachimiak, A]] | ||
| + | [[Category: Li, H]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tan, K]] | ||
| + | [[Category: Mcsg]] | ||
| + | [[Category: PSI, Protein structure initiative]] | ||
| + | [[Category: Unknown function]] | ||
Current revision
The crystal structure of a flagella protein from Yersinia enterocolitica subsp. enterocolitica 8081
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