3k52

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{{Seed}}
 
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[[Image:3k52.png|left|200px]]
 
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==Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IP==
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The line below this paragraph, containing "STRUCTURE_3k52", creates the "Structure Box" on the page.
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<StructureSection load='3k52' size='340' side='right'caption='[[3k52]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3k52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K52 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IP8:ISOPENTENYL+PHOSPHATE'>IP8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3k52| PDB=3k52 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k52 OCA], [https://pdbe.org/3k52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k52 RCSB], [https://www.ebi.ac.uk/pdbsum/3k52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k52 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IP===
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== Function ==
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[https://www.uniprot.org/uniprot/IPK_METJA IPK_METJA] Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate.<ref>PMID:16621811</ref> <ref>PMID:20392112</ref>
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== Evolutionary Conservation ==
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Check<jmol>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k5/3k52_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_20392112}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3K52 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K52 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k52 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:20392112</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Dellas, N.]]
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[[Category: Dellas N]]
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[[Category: Noel, J P.]]
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[[Category: Noel JP]]
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[[Category: Archaea]]
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[[Category: Atp-binding]]
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[[Category: Isopentenyl diphosphate]]
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[[Category: Isopentenyl monophosphate]]
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[[Category: Isoprenoid biosynthesis]]
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[[Category: Methanocaldococcus jannaschii]]
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[[Category: Mevalonate pathway]]
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[[Category: Small molecule kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 7 07:52:06 2010''
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Current revision

Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IP

PDB ID 3k52

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