2cbv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:12, 13 December 2023) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2cbv.gif|left|200px]]<br /><applet load="2cbv" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2cbv, resolution 1.95&Aring;" />
 
-
'''BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CALYSTEGINE B2'''<br />
 
-
==About this Structure==
+
==Beta-glucosidase from Thermotoga maritima in complex with calystegine B2==
-
2CBV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with ACT and CGB as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] Known structural/functional Site: <scene name='pdbsite=AC1:Act Binding Site For Chain B'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CBV OCA].
+
<StructureSection load='2cbv' size='340' side='right'caption='[[2cbv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2cbv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CBV FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CGB:CALYSTEGINE+B2'>CGB</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cbv OCA], [https://pdbe.org/2cbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cbv RCSB], [https://www.ebi.ac.uk/pdbsum/2cbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cbv ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BGLA_THEMA BGLA_THEMA]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cb/2cbv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cbv ConSurf].
 +
<div style="clear:both"></div>
-
==Reference==
+
==See Also==
-
Dissection of conformationally restricted inhibitors binding to a beta-glucosidase., Gloster TM, Madsen R, Davies GJ, Chembiochem. 2006 May;7(5):738-42. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16628756 16628756]
+
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
-
[[Category: Beta-glucosidase]]
+
__TOC__
-
[[Category: Single protein]]
+
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
-
[[Category: Davies, G.J.]]
+
[[Category: Davies GJ]]
-
[[Category: Gloster, T.M.]]
+
[[Category: Gloster TM]]
-
[[Category: Madsen, R.]]
+
[[Category: Madsen R]]
-
[[Category: ACT]]
+
-
[[Category: CGB]]
+
-
[[Category: carbohydrate metabolism]]
+
-
[[Category: cellulose degradation]]
+
-
[[Category: family 1]]
+
-
[[Category: glycosidase]]
+
-
[[Category: glycoside hydrolase]]
+
-
[[Category: hydrolase]]
+
-
[[Category: inhibitor]]
+
-
[[Category: polysaccharide degradation]]
+
-
[[Category: transition state mimic]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 19:17:10 2007''
+

Current revision

Beta-glucosidase from Thermotoga maritima in complex with calystegine B2

PDB ID 2cbv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cbv"
Personal tools