3mkr

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{{Seed}}
 
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[[Image:3mkr.png|left|200px]]
 
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==Crystal structure of yeast alpha/epsilon-COP subcomplex of the COPI vesicular coat==
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The line below this paragraph, containing "STRUCTURE_3mkr", creates the "Structure Box" on the page.
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<StructureSection load='3mkr' size='340' side='right'caption='[[3mkr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3mkr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MKR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkr OCA], [https://pdbe.org/3mkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mkr RCSB], [https://www.ebi.ac.uk/pdbsum/3mkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkr ProSAT]</span></td></tr>
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{{STRUCTURE_3mkr| PDB=3mkr | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of yeast alpha/epsilon-COP subcomplex of the COPI vesicular coat===
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[https://www.uniprot.org/uniprot/COPE_BOVIN COPE_BOVIN] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 20579721 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/3mkr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_20579721}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mkr ConSurf].
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3MKR is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKR OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:20579721</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Goldberg, J.]]
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[[Category: Large Structures]]
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[[Category: Lee, C.]]
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[[Category: Goldberg J]]
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[[Category: Alpha-solenoid]]
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[[Category: Lee C]]
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[[Category: Beta-hairpin]]
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[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:48:20 2010''
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Current revision

Crystal structure of yeast alpha/epsilon-COP subcomplex of the COPI vesicular coat

PDB ID 3mkr

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