2x4l

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{{Seed}}
 
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[[Image:2x4l.jpg|left|200px]]
 
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==Crystal structure of DesE, a ferric-siderophore receptor protein from Streptomyces coelicolor==
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The line below this paragraph, containing "STRUCTURE_2x4l", creates the "Structure Box" on the page.
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<StructureSection load='2x4l' size='340' side='right'caption='[[2x4l]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2x4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X4L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4l OCA], [https://pdbe.org/2x4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x4l RCSB], [https://www.ebi.ac.uk/pdbsum/2x4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x4l ProSAT]</span></td></tr>
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{{STRUCTURE_2x4l| PDB=2x4l | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9L074_STRCO Q9L074_STRCO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/2x4l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x4l ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The Scottish Structural Proteomics Facility was funded to develop a laboratory scale approach to high throughput structure determination. The effort was successful in that over 40 structures were determined. These structures and the methods harnessed to obtain them are reported here. This report reflects on the value of automation but also on the continued requirement for a high degree of scientific and technical expertise. The efficiency of the process poses challenges to the current paradigm of structural analysis and publication. In the 5 year period we published ten peer-reviewed papers reporting structural data arising from the pipeline. Nevertheless, the number of structures solved exceeded our ability to analyse and publish each new finding. By reporting the experimental details and depositing the structures we hope to maximize the impact of the project by allowing others to follow up the relevant biology.
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===CRYSTAL STRUCTURE OF DESE, A FERRIC-SIDEROPHORE RECEPTOR PROTEIN FROM STREPTOMYCES COELICOLOR===
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The Scottish Structural Proteomics Facility: targets, methods and outputs.,Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH J Struct Funct Genomics. 2010 Jun;11(2):167-80. Epub 2010 Apr 24. PMID:20419351<ref>PMID:20419351</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_20419351}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2x4l" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 20419351 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_20419351}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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2X4L is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X4L OCA].
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[[Category: Carter LG]]
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[[Category: Johnson KA]]
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==Reference==
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[[Category: Liu H]]
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<ref group="xtra">PMID:20419351</ref><references group="xtra"/>
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[[Category: Mcmahon SA]]
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[[Category: Streptomyces coelicolor]]
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[[Category: Naismith JH]]
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[[Category: Carter, L G.]]
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[[Category: Oke M]]
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[[Category: Johnson, K A.]]
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[[Category: White MF]]
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[[Category: Liu, H.]]
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[[Category: Mcmahon, S A.]]
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[[Category: Naismith, J H.]]
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[[Category: Oke, M.]]
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[[Category: White, M F.]]
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[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:13:55 2010''
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Current revision

Crystal structure of DesE, a ferric-siderophore receptor protein from Streptomyces coelicolor

PDB ID 2x4l

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