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3i5v

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{{Seed}}
 
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[[Image:3i5v.jpg|left|200px]]
 
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==Crystal structure of beta toxin 275-280 from Staphylococcus aureus==
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The line below this paragraph, containing "STRUCTURE_3i5v", creates the "Structure Box" on the page.
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<StructureSection load='3i5v' size='340' side='right'caption='[[3i5v]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3i5v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_RN4220 Staphylococcus aureus subsp. aureus RN4220]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I5V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene></td></tr>
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{{STRUCTURE_3i5v| PDB=3i5v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5v OCA], [https://pdbe.org/3i5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i5v RCSB], [https://www.ebi.ac.uk/pdbsum/3i5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHLC_STAAU PHLC_STAAU] Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i5v ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of beta toxin 275-280 from Staphylococcus aureus===
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==See Also==
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*[[Hemolysin 3D structures|Hemolysin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3I5V is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rn4220 Staphylococcus aureus rn4220]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5V OCA].
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus RN4220]]
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==Reference==
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[[Category: Huseby M]]
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<ref group="xtra">PMID:17873030</ref><references group="xtra"/>
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[[Category: Kruse AC]]
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[[Category: Staphylococcus aureus rn4220]]
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[[Category: Ohlendorf DH]]
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[[Category: Huseby, M.]]
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[[Category: Shi K]]
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[[Category: Kruse, A C.]]
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[[Category: Ohlendorf, D H.]]
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[[Category: Shi, K.]]
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[[Category: Beta toxin]]
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[[Category: Hemolysin]]
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[[Category: Sphingomyelinase]]
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[[Category: Toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 11 23:53:07 2010''
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Current revision

Crystal structure of beta toxin 275-280 from Staphylococcus aureus

PDB ID 3i5v

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