3hm6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:00, 21 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3hm6.png|left|200px]]
 
-
<!--
+
==Crystal structure of the cytoplasmic domain of human plexin B1==
-
The line below this paragraph, containing "STRUCTURE_3hm6", creates the "Structure Box" on the page.
+
<StructureSection load='3hm6' size='340' side='right'caption='[[3hm6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3hm6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HM6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.402&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
{{STRUCTURE_3hm6| PDB=3hm6 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hm6 OCA], [https://pdbe.org/3hm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hm6 RCSB], [https://www.ebi.ac.uk/pdbsum/3hm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hm6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PLXB1_HUMAN PLXB1_HUMAN] Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.<ref>PMID:12198496</ref> <ref>PMID:12196628</ref> <ref>PMID:15210733</ref> <ref>PMID:19843518</ref> <ref>PMID:20877282</ref> <ref>PMID:21912513</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hm/3hm6_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hm6 ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of the cytoplasmic domain of human plexin B1===
+
==See Also==
-
 
+
*[[Plexin 3D structures|Plexin 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_19843518}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 19843518 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_19843518}}
+
-
 
+
-
==About this Structure==
+
-
3HM6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HM6 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:19843518</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bochkarev, A.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bountra, C.]]
+
[[Category: Bochkarev A]]
-
[[Category: Edwards, A M.]]
+
[[Category: Bountra C]]
-
[[Category: He, H.]]
+
[[Category: Edwards AM]]
-
[[Category: MacKenzie, F.]]
+
[[Category: He H]]
-
[[Category: Park, H.]]
+
[[Category: MacKenzie F]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Park H]]
-
[[Category: Shen, L.]]
+
[[Category: Shen L]]
-
[[Category: Tempel, W.]]
+
[[Category: Tempel W]]
-
[[Category: Tong, Y.]]
+
[[Category: Tong Y]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Cell membrane]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Membrane]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Receptor]]
+
-
[[Category: Secreted]]
+
-
[[Category: Sgc]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Structural genomics consortium]]
+
-
[[Category: Transmembrane]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:05:49 2010''
+

Current revision

Crystal structure of the cytoplasmic domain of human plexin B1

PDB ID 3hm6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3hm6"
Personal tools