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3hj1

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{{Seed}}
 
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[[Image:3hj1.png|left|200px]]
 
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==Minor Editosome-Associated TUTase 1 with bound UTP==
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The line below this paragraph, containing "STRUCTURE_3hj1", creates the "Structure Box" on the page.
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<StructureSection load='3hj1' size='340' side='right'caption='[[3hj1]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3hj1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HJ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HJ1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
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{{STRUCTURE_3hj1| PDB=3hj1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hj1 OCA], [https://pdbe.org/3hj1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hj1 RCSB], [https://www.ebi.ac.uk/pdbsum/3hj1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hj1 ProSAT]</span></td></tr>
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</table>
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===Minor Editosome-Associated TUTase 1 with bound UTP===
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== Function ==
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[https://www.uniprot.org/uniprot/TUT7_TRYBB TUT7_TRYBB] Terminal uridylyltransferase which, as part of the mitochondrial RNA editing core-like complex (RECC-like), is involved in the post-transcriptional editing of mitochondrial RNA, a process involving the addition and deletion of uridine (U) nucleotides in the pre-mRNA (PubMed:19465686). Specifically, catalyzes the addition of U to single-stranded RNA with a preference for a 3'-terminal U and adds the number of Us specified by a guide RNA (gRNA) to precleaved double-stranded RNA editing substrates (PubMed:19465686, PubMed:20403364). Essential for insect and bloodstream developmental forms viability (PubMed:19465686).<ref>PMID:19465686</ref> <ref>PMID:20403364</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_20403364}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 20403364 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/3hj1_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_20403364}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3HJ1 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HJ1 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hj1 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:20403364</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Luecke, H.]]
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[[Category: Luecke H]]
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[[Category: Stagno, J.]]
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[[Category: Stagno J]]
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[[Category: Editosome]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Rna editing]]
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[[Category: Transferase]]
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[[Category: Trypanosoma]]
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[[Category: Tutase]]
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[[Category: Utp-binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:13:47 2010''
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Current revision

Minor Editosome-Associated TUTase 1 with bound UTP

PDB ID 3hj1

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