2kre

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{{Seed}}
 
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[[Image:2kre.png|left|200px]]
 
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==Solution structure of E4B/UFD2A U-Box domain==
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The line below this paragraph, containing "STRUCTURE_2kre", creates the "Structure Box" on the page.
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<StructureSection load='2kre' size='340' side='right'caption='[[2kre]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2kre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kre OCA], [https://pdbe.org/2kre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kre RCSB], [https://www.ebi.ac.uk/pdbsum/2kre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kre ProSAT]</span></td></tr>
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{{STRUCTURE_2kre| PDB=2kre | SCENE= }}
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</table>
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== Function ==
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===Solution structure of E4B/UFD2A U-Box domain===
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[https://www.uniprot.org/uniprot/UBE4B_HUMAN UBE4B_HUMAN] Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_20696396}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 20696396 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2kre_consurf.spt"</scriptWhenChecked>
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-->
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_20696396}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kre ConSurf].
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2KRE is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRE OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:20696396</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Botuyan, M.]]
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[[Category: Large Structures]]
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[[Category: Mer, G.]]
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[[Category: Botuyan M]]
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[[Category: Nomine, Y.]]
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[[Category: Mer G]]
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[[Category: Wasielewski, E.]]
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[[Category: Nomine Y]]
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[[Category: E3 ubiquitin ligase]]
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[[Category: Wasielewski E]]
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[[Category: E4 polyubiquitin chain elongation factor]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding]]
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[[Category: U-box domain]]
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[[Category: Ubl conjugation pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:18:12 2010''
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Current revision

Solution structure of E4B/UFD2A U-Box domain

PDB ID 2kre

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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