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2wu5

From Proteopedia

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{{Seed}}
 
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[[Image:2wu5.jpg|left|200px]]
 
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==Crystal structure of the E. coli succinate:quinone oxidoreductase (SQR) SdhD His71Met mutant==
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The line below this paragraph, containing "STRUCTURE_2wu5", creates the "Structure Box" on the page.
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<StructureSection load='2wu5' size='340' side='right'caption='[[2wu5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2wu5]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WU5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.803&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBE:2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE'>CBE</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=TEO:MALATE+LIKE+INTERMEDIATE'>TEO</scene></td></tr>
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{{STRUCTURE_2wu5| PDB=2wu5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wu5 OCA], [https://pdbe.org/2wu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wu5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wu5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SDHB_ECOLI SDHB_ECOLI] Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/2wu5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wu5 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE E. COLI SUCCINATE:QUINONE OXIDOREDUCTASE (SQR) SDHD HIS71MET MUTANT===
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==See Also==
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*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2WU5 is a 12 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WU5 OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Cecchini, G.]]
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[[Category: Large Structures]]
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[[Category: Iwata, S.]]
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[[Category: Cecchini G]]
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[[Category: Maklashina, E.]]
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[[Category: Iwata S]]
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[[Category: Ruprecht, J.]]
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[[Category: Maklashina E]]
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[[Category: Yankovskaya, V.]]
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[[Category: Ruprecht J]]
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[[Category: Cell inner membrane]]
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[[Category: Yankovskaya V]]
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[[Category: Electron transport]]
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[[Category: Flavoprotein]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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[[Category: Tricarboxylic acid cycle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:50:31 2010''
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Current revision

Crystal structure of the E. coli succinate:quinone oxidoreductase (SQR) SdhD His71Met mutant

PDB ID 2wu5

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