3la3

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{{Seed}}
 
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[[Image:3la3.png|left|200px]]
 
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==Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid==
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The line below this paragraph, containing "STRUCTURE_3la3", creates the "Structure Box" on the page.
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<StructureSection load='3la3' size='340' side='right'caption='[[3la3]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3la3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LA3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2FT:2,2-DIFLUOROPENTANEDIOIC+ACID'>2FT</scene></td></tr>
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{{STRUCTURE_3la3| PDB=3la3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3la3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3la3 OCA], [https://pdbe.org/3la3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3la3 RCSB], [https://www.ebi.ac.uk/pdbsum/3la3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3la3 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid===
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== Function ==
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[https://www.uniprot.org/uniprot/NTCA_NOSS1 NTCA_NOSS1] Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. Has affinity for the xisA upstream region. Binds to a 66 bp region containing three repeats of the consensus recognition sequence 5'-ACATT-3'.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 20616047 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/la/3la3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_20616047}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3LA3 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Anabaena Anabaena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LA3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3la3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:20616047</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Anabaena]]
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[[Category: Large Structures]]
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[[Category: Chen, Y F.]]
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[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
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[[Category: Chen, Y X.]]
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[[Category: Chen YF]]
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[[Category: He, Y X.]]
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[[Category: Chen YX]]
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[[Category: Jiang, Y L.]]
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[[Category: He YX]]
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[[Category: Teng, Y B.]]
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[[Category: Jiang YL]]
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[[Category: Zhang, C C.]]
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[[Category: Teng YB]]
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[[Category: Zhao, M X.]]
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[[Category: Zhang CC]]
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[[Category: Zhou, C Z.]]
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[[Category: Zhao MX]]
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[[Category: Activator]]
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[[Category: Zhou CZ]]
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[[Category: Dna-binding]]
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[[Category: Nitrogen regulator]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:22:12 2010''
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Current revision

Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid

PDB ID 3la3

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