2l2i
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF== | |
| - | + | <StructureSection load='2l2i' size='340' side='right'caption='[[2l2i]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2l2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L2I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l2i OCA], [https://pdbe.org/2l2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l2i RCSB], [https://www.ebi.ac.uk/pdbsum/2l2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l2i ProSAT]</span></td></tr> | |
| - | '' | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TFB1_YEAST TFB1_YEAST] Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.<ref>PMID:7961739</ref> <ref>PMID:8631896</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Di Lello P]] | ||
| + | [[Category: Lafrance-Vanasse J]] | ||
| + | [[Category: Mas C]] | ||
| + | [[Category: Omichinski JG]] | ||
Current revision
NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF
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