3o7q
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3o7q.jpg|left|200px]] | ||
| - | < | + | ==Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation== |
| - | + | <StructureSection load='3o7q' size='340' side='right'caption='[[3o7q]], [[Resolution|resolution]] 3.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3o7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O7Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.143Å</td></tr> | |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7q OCA], [https://pdbe.org/3o7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o7q RCSB], [https://www.ebi.ac.uk/pdbsum/3o7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o7q ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FUCP_ECOLI FUCP_ECOLI] Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose.<ref>PMID:2829831</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/3o7q_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o7q ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Lactose Permease|Lactose Permease]] | |
| - | + | *[[Symporter 3D structures|Symporter 3D structures]] | |
| - | == | + | == References == |
| - | + | <references/> | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Dang | + | </StructureSection> |
| - | [[Category: Sun | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: Wang | + | [[Category: Large Structures]] |
| - | [[Category: Yan | + | [[Category: Dang SY]] |
| - | + | [[Category: Sun LF]] | |
| - | + | [[Category: Wang J]] | |
| - | + | [[Category: Yan N]] | |
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Current revision
Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation
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