1kqf

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{{Seed}}
 
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[[Image:1kqf.png|left|200px]]
 
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==FORMATE DEHYDROGENASE N FROM E. COLI==
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The line below this paragraph, containing "STRUCTURE_1kqf", creates the "Structure Box" on the page.
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<StructureSection load='1kqf' size='340' side='right'caption='[[1kqf]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kqf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KQF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6MO:MOLYBDENUM(VI)+ION'>6MO</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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{{STRUCTURE_1kqf| PDB=1kqf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kqf OCA], [https://pdbe.org/1kqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kqf RCSB], [https://www.ebi.ac.uk/pdbsum/1kqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kqf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FDNG_ECOLI FDNG_ECOLI] Formate dehydrogenase allows E.coli to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. The alpha subunit FdnG contains the formate oxidation site. Electrons are transferred from formate to menaquinone in the gamma subunit (FdnI), through the 4Fe-4S clusters in the beta subunit (FdnH). Formate dehydrogenase-N is part of a system that generates proton motive force, together with the dissimilatory nitrate reductase (Nar).<ref>PMID:11884747</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kq/1kqf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kqf ConSurf].
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<div style="clear:both"></div>
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===FORMATE DEHYDROGENASE N FROM E. COLI===
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==See Also==
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*[[Formate dehydrogenase 3D structures|Formate dehydrogenase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11884747}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11884747 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_11884747}}
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==About this Structure==
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1KQF is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KQF OCA].
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==Reference==
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<ref group="xtra">PMID:11884747</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Formate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Byrne, B.]]
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[[Category: Byrne B]]
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[[Category: Iwata, S.]]
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[[Category: Iwata S]]
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[[Category: Jormakka, M.]]
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[[Category: Jormakka M]]
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[[Category: Tornroth, S.]]
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[[Category: Tornroth S]]
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[[Category: Anaerobic]]
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[[Category: Dehydrogenase]]
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[[Category: Fe4s4]]
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[[Category: Formate]]
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[[Category: Integral membrane protein]]
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[[Category: Iron sulfur cluster]]
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[[Category: Mgd]]
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[[Category: Molybdenum]]
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[[Category: Molybdopterin]]
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[[Category: Molybdopterin guanine dinucleotide]]
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[[Category: Mpt]]
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[[Category: Oxidoreductase]]
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[[Category: Secy]]
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[[Category: Selenium]]
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[[Category: Selenocysteine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:54:37 2010''
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Current revision

FORMATE DEHYDROGENASE N FROM E. COLI

PDB ID 1kqf

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