3ne0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:29, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3ne0.jpg|left|200px]]
 
-
<!--
+
==Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation==
-
The line below this paragraph, containing "STRUCTURE_3ne0", creates the "Structure Box" on the page.
+
<StructureSection load='3ne0' size='340' side='right'caption='[[3ne0]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3ne0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NE0 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ne0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ne0 OCA], [https://pdbe.org/3ne0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ne0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ne0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ne0 ProSAT]</span></td></tr>
-
{{STRUCTURE_3ne0| PDB=3ne0 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation===
+
[https://www.uniprot.org/uniprot/RIPA_MYCTU RIPA_MYCTU] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_20826344}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 20826344 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/3ne0_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_20826344}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ne0 ConSurf].
-
3NE0 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NE0 OCA].
+
<div style="clear:both"></div>
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:20826344</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Mycobacterium tuberculosis]]
+
</StructureSection>
-
[[Category: Berisio, R.]]
+
[[Category: Large Structures]]
-
[[Category: Ruggiero, A.]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Squeglia, F.]]
+
[[Category: Berisio R]]
-
[[Category: Cell wall]]
+
[[Category: Ruggiero A]]
-
[[Category: Hydrolase]]
+
[[Category: Squeglia F]]
-
[[Category: Peptidoglycan]]
+
-
[[Category: Tuberculosis]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:47:22 2010''
+

Current revision

Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation

PDB ID 3ne0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ne0"
Personal tools