2e7d
From Proteopedia
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(New page: 200px<br /><applet load="2e7d" size="350" color="white" frame="true" align="right" spinBox="true" caption="2e7d, resolution 2.20Å" /> '''Crystal structure of...) |
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| - | [[Image:2e7d.jpg|left|200px]]<br /><applet load="2e7d" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2e7d, resolution 2.20Å" /> | ||
| - | '''Crystal structure of a NEAT domain from Staphylococcus aureus'''<br /> | ||
| - | == | + | ==Crystal structure of a NEAT domain from Staphylococcus aureus== |
| - | + | <StructureSection load='2e7d' size='340' side='right'caption='[[2e7d]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| + | <table><tr><td colspan='2'>[[2e7d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E7D FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7d OCA], [https://pdbe.org/2e7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e7d RCSB], [https://www.ebi.ac.uk/pdbsum/2e7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7d ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7d_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7d ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Kumagai | + | [[Category: Kumagai I]] |
| - | [[Category: Suenaga | + | [[Category: Suenaga A]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka I]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka Y]] |
| - | [[Category: Tsumoto | + | [[Category: Tsumoto K]] |
| - | [[Category: Yao | + | [[Category: Yao M]] |
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Current revision
Crystal structure of a NEAT domain from Staphylococcus aureus
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