2kzg

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{{Seed}}
 
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[[Image:2kzg.jpg|left|200px]]
 
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==A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution==
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The line below this paragraph, containing "STRUCTURE_2kzg", creates the "Structure Box" on the page.
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<StructureSection load='2kzg' size='340' side='right'caption='[[2kzg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2kzg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KZG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kzg OCA], [https://pdbe.org/2kzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kzg RCSB], [https://www.ebi.ac.uk/pdbsum/2kzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kzg ProSAT]</span></td></tr>
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{{STRUCTURE_2kzg| PDB=2kzg | SCENE= }}
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</table>
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== Function ==
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===A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution===
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[https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_20829478}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 20829478 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/2kzg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_20829478}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kzg ConSurf].
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2KZG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KZG OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:20829478</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Banachewicz, W.]]
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[[Category: Large Structures]]
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[[Category: Fersht, A R.]]
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[[Category: Banachewicz W]]
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[[Category: Kay, L E.]]
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[[Category: Fersht AR]]
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[[Category: Korzhnev, D M.]]
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[[Category: Kay LE]]
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[[Category: Religa, T L.]]
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[[Category: Korzhnev DM]]
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[[Category: Cpmg]]
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[[Category: Religa TL]]
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[[Category: Folding intermediate]]
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[[Category: Low populated]]
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[[Category: Protein binding]]
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[[Category: Relaxation dispersion]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 08:09:11 2010''
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Current revision

A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution

PDB ID 2kzg

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