2xsd
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2xsd is ON HOLD until Paper Publication Authors: Jauch, R., Hua, C.S., Ng, C.K.L., Kolatkar, P.R. Description: Crystal Structure of the dimeric Oct...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA== | |
| - | + | <StructureSection load='2xsd' size='340' side='right'caption='[[2xsd]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2xsd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XSD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.049Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | '' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xsd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xsd OCA], [https://pdbe.org/2xsd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xsd RCSB], [https://www.ebi.ac.uk/pdbsum/2xsd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xsd ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PO3F1_MOUSE PO3F1_MOUSE] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Choo SH]] | ||
| + | [[Category: Jauch R]] | ||
| + | [[Category: Kolatkar PR]] | ||
| + | [[Category: Ng CKL]] | ||
Current revision
Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA
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