3ngk

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{{Seed}}
 
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[[Image:3ngk.jpg|left|200px]]
 
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==PduA from Salmonella enterica Typhimurium==
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The line below this paragraph, containing "STRUCTURE_3ngk", creates the "Structure Box" on the page.
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<StructureSection load='3ngk' size='340' side='right'caption='[[3ngk]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ngk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NGK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2608&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ngk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngk OCA], [https://pdbe.org/3ngk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ngk RCSB], [https://www.ebi.ac.uk/pdbsum/3ngk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ngk ProSAT]</span></td></tr>
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{{STRUCTURE_3ngk| PDB=3ngk | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDUA_SALTY PDUA_SALTY]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ng/3ngk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ngk ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Bacterial microcompartments are a functionally diverse group of proteinaceous organelles that confine specific reaction pathways in the cell within a thin protein-based shell. The propanediol utilizing (Pdu) microcompartment contains the reactions for metabolizing 1,2-propanediol in certain enteric bacteria, including Salmonella. The Pdu shell is assembled from a few thousand protein subunits of several different types. Here we report the crystal structures of two key shell proteins, PduA and PduT. The crystal structures offer insights into the mechanisms of Pdu microcompartment assembly and molecular transport across the shell. PduA forms a symmetric homohexamer whose central pore appears tailored for facilitating transport of the 1,2-propanediol substrate. PduT is a novel, tandem domain shell protein that assembles as a pseudohexameric homotrimer. Its structure reveals an unexpected site for binding an [Fe-S] cluster at the center of the PduT pore. The location of a metal redox cofactor in the pore of a shell protein suggests a novel mechanism for either transferring redox equivalents across the shell or for regenerating luminal [Fe-S] clusters.
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===PduA from Salmonella enterica Typhimurium===
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Structural insights into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell.,Crowley CS, Cascio D, Sawaya MR, Kopstein JS, Bobik TA, Yeates TO J Biol Chem. 2010 Sep 24. PMID:20870711<ref>PMID:20870711</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_20870711}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3ngk" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 20870711 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_20870711}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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3NGK is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGK OCA].
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Cascio D]]
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==Reference==
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[[Category: Crowley CS]]
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<ref group="xtra">PMID:20870711</ref><references group="xtra"/>
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[[Category: Sawaya MR]]
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Yeates TO]]
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[[Category: Cascio, D.]]
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[[Category: Crowley, C S.]]
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[[Category: Sawaya, M R.]]
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[[Category: Yeates, T O.]]
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[[Category: Bmc shell protein]]
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[[Category: Carboxysome]]
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[[Category: Pdu]]
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[[Category: Propanediol]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:06:35 2010''
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Current revision

PduA from Salmonella enterica Typhimurium

PDB ID 3ngk

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OCA

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