2osb

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(New page: 200px<br /><applet load="2osb" size="350" color="white" frame="true" align="right" spinBox="true" caption="2osb, resolution 1.800&Aring;" /> '''Crystal structure o...)
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[[Image:2osb.jpg|left|200px]]<br /><applet load="2osb" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2osb, resolution 1.800&Aring;" />
 
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'''Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q16L/Q199R/)'''<br />
 
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==About this Structure==
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==Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q16L/Q199R/)==
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2OSB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=AP5:'>AP5</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenylate_kinase Adenylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSB OCA].
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<StructureSection load='2osb' size='340' side='right'caption='[[2osb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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[[Category: Adenylate kinase]]
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== Structural highlights ==
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[[Category: Bacillus subtilis]]
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<table><tr><td colspan='2'>[[2osb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OSB FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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[[Category: Counago, R.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AP5:BIS(ADENOSINE)-5-PENTAPHOSPHATE'>AP5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Myers, J.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2osb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osb OCA], [https://pdbe.org/2osb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2osb RCSB], [https://www.ebi.ac.uk/pdbsum/2osb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2osb ProSAT]</span></td></tr>
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[[Category: Shamoo, Y.]]
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</table>
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[[Category: Wilson, C.J.]]
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== Function ==
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[[Category: Wu, G.]]
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[https://www.uniprot.org/uniprot/KAD_BACSU KAD_BACSU] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in the energy metabolism and nucleotide synthesis, is essential for maintenance and cell growth.
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[[Category: AP5]]
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== Evolutionary Conservation ==
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[[Category: MG]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: ZN]]
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Check<jmol>
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[[Category: adenylate kinase]]
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<jmolCheckbox>
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[[Category: directed evolution]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2osb_consurf.spt"</scriptWhenChecked>
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[[Category: experimental adaptive evolution]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: thermostability]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: transferase]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2osb ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:06:22 2008''
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==See Also==
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*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Bacillus subtilis]]
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[[Category: Large Structures]]
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[[Category: Counago R]]
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[[Category: Myers J]]
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[[Category: Shamoo Y]]
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[[Category: Wilson CJ]]
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[[Category: Wu G]]

Current revision

Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q16L/Q199R/)

PDB ID 2osb

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