3nh8

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'''Unreleased structure'''
 
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The entry 3nh8 is ON HOLD until Paper Publication
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==Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine==
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<StructureSection load='3nh8' size='340' side='right'caption='[[3nh8]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3nh8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NH8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.802&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DC2:N-ACETYL-S-[(1S)-1,2-DICHLOROETHYL]-L-CYSTEINE'>DC2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nh8 OCA], [https://pdbe.org/3nh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nh8 RCSB], [https://www.ebi.ac.uk/pdbsum/3nh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nh8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACY3_MOUSE ACY3_MOUSE] Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.<ref>PMID:14656720</ref> <ref>PMID:17012540</ref>
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Authors: Hsieh, J.M., Tsirulnikov, K., Sawaya, M.R., Magilnick, N., Abuladze, N., Kurtz, I., Abramson, J., Pushkin, A.
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==See Also==
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*[[Aminoacylase 3D structures|Aminoacylase 3D structures]]
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Description: Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine
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*[[Aspartoacylase 3D structures|Aspartoacylase 3D structures]]
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== References ==
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:29:18 2010''
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Abramson J]]
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[[Category: Abuladze N]]
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[[Category: Hsieh JM]]
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[[Category: Kurtz I]]
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[[Category: Magilnick N]]
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[[Category: Pushkin A]]
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[[Category: Sawaya MR]]
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[[Category: Tsirulnikov K]]

Current revision

Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine

PDB ID 3nh8

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