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3p2q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3p2q is ON HOLD Authors: Weeks, A.M., Coyle, S.M., Jinek, M., Doudna, J.A., Chang, M.C.Y. Description: Crystal structure of the fluoroacetyl-CoA-sp...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK== | |
| + | <StructureSection load='3p2q' size='340' side='right'caption='[[3p2q]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3p2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_cattleya Streptomyces cattleya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P2Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p2q OCA], [https://pdbe.org/3p2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p2q RCSB], [https://www.ebi.ac.uk/pdbsum/3p2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p2q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FLK_STRCT FLK_STRCT] Hydrolyzes fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance. Can not use acetyl-CoA as substrate.<ref>PMID:16720268</ref> <ref>PMID:20836570</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Thioesterase 3D structures|Thioesterase 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptomyces cattleya]] | ||
| + | [[Category: Chang MCY]] | ||
| + | [[Category: Coyle SM]] | ||
| + | [[Category: Doudna JA]] | ||
| + | [[Category: Jinek M]] | ||
| + | [[Category: Weeks AM]] | ||
Current revision
Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK
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