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3oky

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{{Seed}}
 
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[[Image:3oky.jpg|left|200px]]
 
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==Plexin A2 in complex with Semaphorin 6A==
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The line below this paragraph, containing "STRUCTURE_3oky", creates the "Structure Box" on the page.
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<StructureSection load='3oky' size='340' side='right'caption='[[3oky]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3oky]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OKY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.195&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_3oky| PDB=3oky | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oky OCA], [https://pdbe.org/3oky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oky RCSB], [https://www.ebi.ac.uk/pdbsum/3oky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oky ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PLXA2_MOUSE PLXA2_MOUSE] Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:10520994</ref> <ref>PMID:10781943</ref> <ref>PMID:20877282</ref>
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===Plexin A2 in complex with Semaphorin 6A===
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==See Also==
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*[[Plexin 3D structures|Plexin 3D structures]]
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*[[Semaphorin 3D structures|Semaphorin 3D structures]]
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== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 20877282 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_20877282}}
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[[Category: Large Structures]]
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==About this Structure==
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3OKY is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKY OCA].
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==Reference==
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<ref group="xtra">PMID:20877282</ref><references group="xtra"/>
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bell, C H.]]
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[[Category: Bell CH]]
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[[Category: Janssen, B J.C.]]
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[[Category: Janssen BJC]]
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[[Category: Jones, E Y.]]
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[[Category: Jones EY]]
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[[Category: Robinson, R A.]]
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[[Category: Robinson RA]]
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[[Category: Siebold, C.]]
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[[Category: Siebold C]]
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[[Category: Cell-cell signalling]]
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[[Category: Ligand]]
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[[Category: Sema-domain]]
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[[Category: Signaling protein]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:51:04 2010''
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Current revision

Plexin A2 in complex with Semaphorin 6A

PDB ID 3oky

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