3p5p
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3p5p is ON HOLD Authors: Koksal, M., Christianson, D.W. Description: Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) '...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate== | |
| - | + | <StructureSection load='3p5p' size='340' side='right'caption='[[3p5p]], [[Resolution|resolution]] 1.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3p5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Taxus_brevifolia Taxus brevifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P5P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.816Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3C:2-(METHYL{2-[(1S,4AS,8AS)-5,5,8A-TRIMETHYL-2-METHYLIDENEDECAHYDRONAPHTHALEN-1-YL]ETHYL}AMINO)ETHYL+TRIHYDROGEN+DIPHOSPHATE'>A3C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | '' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p5p OCA], [https://pdbe.org/3p5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p5p RCSB], [https://www.ebi.ac.uk/pdbsum/3p5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p5p ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TASY_TAXBR TASY_TAXBR] Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Taxus brevifolia]] | ||
| + | [[Category: Christianson DW]] | ||
| + | [[Category: Koksal M]] | ||
Current revision
Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate
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