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3km8

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{{Seed}}
 
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[[Image:3km8.jpg|left|200px]]
 
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==Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine==
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The line below this paragraph, containing "STRUCTURE_3km8", creates the "Structure Box" on the page.
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<StructureSection load='3km8' size='340' side='right'caption='[[3km8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3km8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KM8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9DI:9-DEAZAINOSINE'>9DI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3km8| PDB=3km8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3km8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3km8 OCA], [https://pdbe.org/3km8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3km8 RCSB], [https://www.ebi.ac.uk/pdbsum/3km8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3km8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ADA_MOUSE ADA_MOUSE] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity).
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===Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine===
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==See Also==
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*[[Adenosine deaminase 3D structures|Adenosine deaminase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3KM8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA].
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[[Category: Large Structures]]
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[[Category: Adenosine deaminase]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Fan, X.]]
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[[Category: Fan X]]
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[[Category: Gao, Y.]]
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[[Category: Gao Y]]
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[[Category: Cyclicamidine]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide metabolism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 20 06:36:10 2010''
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Current revision

Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine

PDB ID 3km8

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