1oj8

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{{Seed}}
 
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[[Image:1oj8.png|left|200px]]
 
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==Novel and retro Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with d(ApCpGpA) and (2',5'CpG)==
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The line below this paragraph, containing "STRUCTURE_1oj8", creates the "Structure Box" on the page.
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<StructureSection load='1oj8' size='340' side='right'caption='[[1oj8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1oj8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_catesbeianus Lithobates catesbeianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OJ8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1oj8| PDB=1oj8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oj8 OCA], [https://pdbe.org/1oj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oj8 RCSB], [https://www.ebi.ac.uk/pdbsum/1oj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oj8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9DFY5_AQUCT Q9DFY5_AQUCT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oj/1oj8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oj8 ConSurf].
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<div style="clear:both"></div>
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===NOVEL AND RETRO BINDING MODES IN CYTOTOXIC RIBONUCLEASES FROM RANA CATESBEIANA OF TWO CRYSTAL STRUCTURES COMPLEXED WITH D(APCPGPA) AND (2',5'CPG)===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1OJ8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rana_catesbeiana Rana catesbeiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJ8 OCA].
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[[Category: Large Structures]]
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[[Category: Rana catesbeiana]]
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[[Category: Lithobates catesbeianus]]
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[[Category: Chen, L Y.]]
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[[Category: Chen L-Y]]
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[[Category: Cheng, P T.]]
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[[Category: Cheng P-T]]
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[[Category: Liao, Y D.]]
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[[Category: Liao Y-D]]
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[[Category: Liu, J H.]]
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[[Category: Liu J-H]]
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[[Category: Sun, Y J.]]
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[[Category: Sun Y-J]]
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[[Category: Tsai, C J.]]
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[[Category: Tsai C-J]]
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[[Category: Anti-tumor activity]]
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[[Category: Cytotoxic ribonuclease]]
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[[Category: Hydrolase]]
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[[Category: Sialic binding and nucleotide binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:28:10 2010''
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Current revision

Novel and retro Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with d(ApCpGpA) and (2',5'CpG)

PDB ID 1oj8

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OCA

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