3ke6

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{{Seed}}
 
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[[Image:3ke6.jpg|left|200px]]
 
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==The crystal structure of the RsbU and RsbW domains of Rv1364c from Mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_3ke6", creates the "Structure Box" on the page.
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<StructureSection load='3ke6' size='340' side='right'caption='[[3ke6]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ke6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KE6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3ke6| PDB=3ke6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ke6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ke6 OCA], [https://pdbe.org/3ke6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ke6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ke6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ke6 ProSAT]</span></td></tr>
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</table>
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===The crystal structure of the RsbU and RsbW domains of Rv1364c from Mycobacterium tuberculosis===
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== Function ==
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[https://www.uniprot.org/uniprot/MTDRP_MYCTU MTDRP_MYCTU] Primarily acts as an independent SigF regulator that is sensitive to the osmosensory signal, mediating the cross talk of PknD with the SigF regulon (PubMed:30642988). Possesses both phosphatase and kinase activities (PubMed:30642988, PubMed:19700407). The kinase domain functions as a classic anti-sigma factor-like kinase to phosphorylate the anti-anti-sigma factor domain at the canonical regulatory site, and the phosphatase domain antagonizes this activity (PubMed:19700407).<ref>PMID:19700407</ref> <ref>PMID:30642988</ref>
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== References ==
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==About this Structure==
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<references/>
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3KE6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KE6 OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: King-Scott, J.]]
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[[Category: King-Scott J]]
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[[Category: Panjikar, S.]]
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[[Category: Panjikar S]]
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[[Category: Tucker, P A.]]
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[[Category: Tucker PA]]
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[[Category: Anti-sigma factor]]
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[[Category: Anti-sigma factor antagonist]]
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[[Category: Atpase]]
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[[Category: Phosphatase]]
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[[Category: Pp2c]]
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[[Category: Serine kinase]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:47:01 2010''
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Current revision

The crystal structure of the RsbU and RsbW domains of Rv1364c from Mycobacterium tuberculosis

PDB ID 3ke6

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