3hup

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:58, 6 November 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3hup.png|left|200px]]
 
-
<!--
+
==High-resolution structure of the extracellular domain of human CD69==
-
The line below this paragraph, containing "STRUCTURE_3hup", creates the "Structure Box" on the page.
+
<StructureSection load='3hup' size='340' side='right'caption='[[3hup]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3hup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HUP FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.371&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
{{STRUCTURE_3hup| PDB=3hup | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hup OCA], [https://pdbe.org/3hup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hup RCSB], [https://www.ebi.ac.uk/pdbsum/3hup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hup ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CD69_HUMAN CD69_HUMAN] Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/3hup_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hup ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The structure of the extracellular domain of human CD69 has been determined by single-crystal X-ray diffraction. The structure refined to 1.37 A resolution provides further details of the overall structure and the asymmetric interface between the monomers in the native dimer. The protein was crystallized using di[poly(ethylene glycol)] adipate, which also served as a cryoprotectant. This is the first report of a crystal structure determined using crystals grown with this polymer.
-
===High-resolution structure of the extracellular domain of human CD69===
+
The high-resolution structure of the extracellular domain of human CD69 using a novel polymer.,Kolenko P, Skalova T, Vanek O, Stepankova A, Duskova J, Hasek J, Bezouska K, Dohnalek J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1258-60. Epub 2009 Nov 27. PMID:20054122<ref>PMID:20054122</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3hup" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_20054122}}, adds the Publication Abstract to the page
+
*[[CD69|CD69]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 20054122 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_20054122}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
3HUP is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUP OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:20054122</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Bezouska, K.]]
+
[[Category: Large Structures]]
-
[[Category: Dohnalek, J.]]
+
[[Category: Bezouska K]]
-
[[Category: Duskova, J.]]
+
[[Category: Dohnalek J]]
-
[[Category: Hasek, J.]]
+
[[Category: Duskova J]]
-
[[Category: Kolenko, P.]]
+
[[Category: Hasek J]]
-
[[Category: Skalova, T.]]
+
[[Category: Kolenko P]]
-
[[Category: Vanek, O.]]
+
[[Category: Skalova T]]
-
[[Category: C-type lectin-like domain]]
+
[[Category: Vanek O]]
-
[[Category: Disulfide bond]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Immune system]]
+
-
[[Category: Lectin]]
+
-
[[Category: Membrane]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Signal-anchor]]
+
-
[[Category: Transmembrane]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:21:41 2010''
+

Current revision

High-resolution structure of the extracellular domain of human CD69

PDB ID 3hup

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3hup"
Personal tools