3pgy

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{{Seed}}
 
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[[Image:3pgy.jpg|left|200px]]
 
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==Serine hydroxymethyltransferase from Staphylococcus aureus, S95P mutant.==
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The line below this paragraph, containing "STRUCTURE_3pgy", creates the "Structure Box" on the page.
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<StructureSection load='3pgy' size='340' side='right'caption='[[3pgy]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pgy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PGY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
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{{STRUCTURE_3pgy| PDB=3pgy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pgy OCA], [https://pdbe.org/3pgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pgy RCSB], [https://www.ebi.ac.uk/pdbsum/3pgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pgy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLYA_STAAC GLYA_STAAC] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051]
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===Serine hydroxymethyltransferase from Staphylococcus aureus, S95P mutant.===
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==See Also==
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*[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3PGY is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PGY OCA].
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[[Category: Large Structures]]
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[[Category: Glycine hydroxymethyltransferase]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Staphylococcus aureus]]
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[[Category: Anderson WF]]
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[[Category: Anderson, W F.]]
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[[Category: Joachimiak A]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Kwon K]]
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[[Category: Joachimiak, A.]]
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[[Category: Makowska-Grzyska M]]
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[[Category: Kwon, K.]]
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[[Category: Osipiuk J]]
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[[Category: Makowska-Grzyska, M.]]
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[[Category: Osipiuk, J.]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: Idp00749]]
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[[Category: Serine hydroxymethyltransferase]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:56:58 2010''
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Current revision

Serine hydroxymethyltransferase from Staphylococcus aureus, S95P mutant.

PDB ID 3pgy

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