Sandbox c20
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hola como estas? | hola como estas? | ||
bien y vos? | bien y vos? | ||
| - | <Structure load=' | + | <Structure load='1ACJ' size='500' frame='true' align='right' caption='Insert caption here' /> |
| + | 1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | ||
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| + | Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor. | ||
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| + | It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease. | ||
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| + | Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). | ||
| + | [[http://proteopedia.org/wiki/index.php/User:Jaime_Prilusky/How_do_we_get_the_oxygen_we_breathe]] | ||
| + | <scene name='Sandbox_c20/Sitios_de_union_de_tartrina/1'>W84 and F330</scene> | ||
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| + | Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site go | ||
| + | <ref>PMID 8415649</ref> | ||
| + | <references/> | ||
Current revision
hola como estas? bien y vos?
|
1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine.
Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor.
It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). [[1]]
Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site go [1]
